The role of type 1 angiotensin 2 receptor polymorphism in asthmatic patients
نویسندگان
چکیده
Background It is known that type 1 angiotensin II (Ang II) receptor (AGTR1) could be related with the pathogenesis of bronchial asthma. It is involved in Th polarization, through different signaling pathways modulating allergic airway inflammation, and also may participate in airway remodeling and bronchoconstriction, that could be related with AGTR1 polymorphism. The purpose of this study is to analyze the association between AGTR1 1166A/C (rs5186) gene polymorphism with asthma severity.
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